For cat lovers, a cat allergy poses a particularly heartbreaking dilemma. Imagine finding yourself sneezing uncontrollably, with a runny nose, itchy eyes, skin rashes, or even experiencing asthma attacks just by being near your beloved furry companion. Surprisingly, this is a common issue with about 1 in 10 people, a significant 10% of the global […]
Gene therapy holds immense promise for treating a wide array of genetic disorders, but one of its biggest challenges remains the delivery of therapeutic materials to target cells. Current delivery vectors, such as lentivirus, adenovirus, adeno-associated virus (AAV), and lipid nanoparticles (LNPs), each come with limitations. Some randomly integrate into the genome, leading to unintended […]
In the November 17, 2021 issue of Science Translational Medicine, Sajid et al. reported an mRNA vaccine encoding a tick salivary protein. Normally, the bite of a host is not detectable due to the unique components of tick-secreted saliva. Tick bites in I9ISP-immunized guinea pigs, on the other hand, cause considerable erythema or pruritus within a […]
The vast majority of cancer cells exhibit either a deficit or an excess of certain chromosomes, a condition known as aneuploidy. Since its discovery in the late 19th century, researchers have debated whether aneuploidy actively fuels cancer or is merely a byproduct of the rapid growth of cancer cells. Studying DNA changes on such a […]
