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Understanding Circular Dichroism Spectroscopy in Biochemistry

What is Circular Dichroism? Circular dichroism is an optical phenomenon that arises from the interaction of chiral molecules with circularly polarized light. It refers to the difference in absorbance of left- and right-circularly polarized light by a sample. Chirality is a property of molecules that are non-superimposable on their mirror image. In the world of biomolecules, […]

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Principles, Processes and Types of Molecular Docking

What is molecular docking? Molecular docking is an important method for structure-based drug design and screening by studying the interaction of ligand and receptor molecules and predicting their affinity and binding modes. Elements in molecular docking (Hernández et al., 2013) Why molecular docking? Identification of protein-protein interactions (PPIs) is of great importance for revealing important signaling pathways, studying protein […]

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How to Detect Steroid Hormones?

What are steroid hormones? Steroid hormones are a group of compounds with a cyclopentane polyhydrophenanthrene structure formed by cholesterol catalyzed by cytochrome P450 enzymes. Steroid hormones are divided into four main groups: progesterone, corticosteroid, estrogen, and androgen. Steroid hormones play an important role in regulating human metabolism, maintaining the stability of the internal environment, growth, […]

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Phosphatidylcholine: Function and Detection

Phosphatidylcholine (PC) consists of a glycerol group, a fatty acid group, a phosphate group and choline. The fatty acid groups often include palmitic acid, stearic acid, oleic acid, linoleic acid, linolenic acid, and arachidonic acid. Function and application of phosphatidylcholine PC not only provides essential phosphorus for human growth and development, but also is a major […]

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